Despite numerous developed therapies, keloid treatment has remained a challenging clinical problem. This might be due to the fact that the mechanisms of development of keloids have not been completely understood [9]. Laser therapy, surgical removal, radiation therapy, silicone gel, cryosurgery, intralesional injection of various agents, and occlusive dressing have all been used either alone or in various combinations [10]. However, evolution of different therapies has not significantly improved their success rates. In addition, each method has its own limitations such as high cost, poor efficacy, recurrence, and adverse effects (such as malignancy).