Auscultation and percussion of the

Auscultation and percussion of the lungs show areas of dulness and diminished intensity in the breath sounds throughout these areas；the preliminary formation of such patches being heralded by fine crepitations，not unlike those of the earliest stages of pneumonia.These areas alter in position，from day to day，the affected portions of the lungs returning to normal in the course of a few hours.Expectoration，when present，is scanty.No organisms which could be connected with the symptoms have been found in it.Pulse is slow in proportion to the height of the fever.Heart normal.Gastric symptoms，when present，may be quite acute and distressing.The tongue is coated with a thick yellowish-white fur；anorexia is pronounced.There may be either diarrhœa or constipation.If the former the stools are usually of a dysenteric type，frequent and containing blood and mucous，the passage of which is attended by a certain amount of pain and tenesmus.Examination of the stools for helminths has，so far，proved unenlightening.In one case bodies like filaria，but of various lengths，were found in the honey-coloured mucus from the bowel.Sheath-like bodies lay beside them.These objects were motionless when seen.Bodies and sheaths stained badly with hæmatoxylin and showed no formation.They were found in one case and on one occasion only.The blood shows a pronounced and increasing eosinophilia，which may reach as high as 40 cent.Mononuclears are slightly increased，6 per cent.to 8 per cent.In the early stages there is a leucocytosis，but this is replaced if the disease drags on by a leucopenia；the total whites falling to 6，000 per c.m.or thereabouts.At the same time there is usually a reduction in the red cells of a million or so in the c.m.The hæmoglobin in the above cases was not estimated，but clinically the grade of anæmia appeared less than that associated with benign malarias.No parasites of any kind were discovered in the blood，though a careful search was made of wet and dry specimens taken at all times of the day and night.An examination of the fluid from the wheals was also negative.