Bleomycin vs triamcinolone acetonidecombined with 5-fluorouracil Two studies showed the recurrences in patients treated with bleomycin or TAC plus 5-FU for treating keloid or hypertrophic scar (Figure 4).16,17 The bleomycin group had relatively lower recurrence compared to the TAC plus 5-FU group, but there was no statistical difference (RR: 0.24, 95% CI: 0.00-53.00, P = .6072).